top of page

Kratom Addiction: Balancing Benefits and Risks for a Healthier Future

Kratom, a natural plant with a rich history of traditional use in Southeast Asia, has gained global attention for its potential benefits in pain relief, mood enhancement, and managing opioid withdrawal. As we have explored, Kratom's journey is a complex one, marked by its capacity to offer significant therapeutic benefits while also posing risks of addiction and dependence. Understanding this dual nature is essential for leveraging Kratom's potential in a way that maximizes benefits and minimizes harm.

Kratom leaves, kratom tea, kratom powder, kratom capsules, and kratom flower buds sit on a table

The Reality of Kratom Addiction

Kratom addiction typically develops when the substance is used frequently and in high doses over an extended period. While some users consume Kratom sporadically without developing a dependency, others find themselves increasingly reliant on it to manage pain, enhance mood, or alleviate withdrawal symptoms from other substances.

According to a 2019 study published in the journal "Drug and Alcohol Dependence," an estimated 3-4% of Kratom users develop a dependence on the substance. The risk of addiction appears to correlate with the dosage and frequency of use. For instance, daily use of high doses (over 5 grams per dose) for several months significantly increases the likelihood of developing dependency symptoms.

Benefits of Kratom Use:

1. Pain Relief: Kratom has been used traditionally to alleviate chronic pain, with many users finding it effective for conditions such as arthritis, fibromyalgia, and back pain.

2. Mood Enhancement: At lower doses, Kratom can act as a stimulant, providing increased energy, alertness, and a sense of well-being.

3. Opioid Withdrawal Aid: Kratom is often used as a natural alternative to manage withdrawal symptoms from opioids, helping to ease the transition off more potent and harmful substances.

Repercussions of Kratom Use:

1. Physical Dependence: Prolonged and heavy use of Kratom can lead to physical dependence, where the body becomes accustomed to the presence of the substance and experiences withdrawal symptoms when it is not available.

2. Tolerance Development: Over time, users may find that they need to consume higher doses of Kratom to achieve the same effects, leading to increased consumption and a higher risk of addiction.

3. Withdrawal Symptoms: Kratom withdrawal can be uncomfortable and may include symptoms such as muscle aches, insomnia, irritability, and mood swings. These symptoms can make it challenging for users to quit or reduce their usage.

4. Potential for Abuse: While Kratom is generally considered safer than opioids, it still has the potential for abuse, particularly among individuals with a history of substance use disorders.

Feeling split, blurred image of man shaking head

The Biochemistry of Kratom Addiction

Kratom contains several active compounds, known as alkaloids, that exert a range of effects on the brain and body. The primary alkaloids responsible for Kratom's effects are mitragynine and 7-hydroxymitragynine. These compounds interact with various receptors in the brain, including opioid receptors, which play a significant role in pain perception, mood regulation, and addictive behaviors.

Mitragynine: The most abundant alkaloid in Kratom, mitragynine, acts as a partial agonist at the mu-opioid receptors. This means it activates these receptors but not to the same extent as traditional opioids like morphine or heroin. Mitragynine also interacts with other receptors, including delta-opioid receptors and adrenergic receptors, contributing to its stimulant effects at lower doses and sedative effects at higher doses.

7-Hydroxymitragynine: Although present in smaller quantities, 7-hydroxymitragynine is significantly more potent than mitragynine. It is a strong agonist at mu-opioid receptors, with an affinity comparable to that of traditional opioids. This alkaloid is primarily responsible for Kratom's pain-relieving and euphoric effects, but it also contributes to the risk of addiction.

Mechanisms of Action:

Dopamine Release: Dopamine is a key player in the brain's reward system. When Kratom stimulates opioid receptors, it leads to an increase in dopamine levels, producing feelings of pleasure and reward. This mechanism is similar to that of other addictive substances, including opioids, which can reinforce the desire to continue using Kratom.

Serotonin Interaction: Kratom's interaction with serotonin receptors also plays a role in its mood-enhancing effects. Serotonin is involved in regulating mood, anxiety, and overall well-being. By modulating serotonin levels, Kratom can provide relief from anxiety and depression, further contributing to its appeal.

Pain Relief: The pain-relieving properties of Kratom are primarily mediated through its action on opioid receptors. By mimicking the effects of endogenous opioids (natural pain-relieving chemicals produced by the body), Kratom can effectively reduce pain, making it a valuable tool for those dealing with chronic pain conditions. However, this same mechanism also increases the risk of dependence and addiction.

Recent studies have shed light on the biochemistry of Kratom and its potential for addiction. A 2018 study published in the journal "Neuropharmacology" investigated the effects of mitragynine and 7-hydroxymitragynine on opioid receptors. The researchers found that while both alkaloids activated mu-opioid receptors, 7-hydroxymitragynine had a significantly higher efficacy, suggesting a greater potential for addiction.

Another study, published in the "Journal of Medicinal Chemistry" in 2019, explored the structure-activity relationships of Kratom alkaloids. The researchers identified specific structural features that contribute to the high affinity of 7-hydroxymitragynine for opioid receptors, providing insights into why this alkaloid is particularly potent and potentially addictive.

Man sits alone on the beach contemplating

Managing and Recovering from Kratom Addiction

Recognizing the signs of Kratom addiction is the first step toward recovery. Common indicators include increased tolerance, withdrawal symptoms, compulsive use, and cravings. Once addiction is identified, various strategies can be employed to reduce usage and end dependence.

1. Tapering Down: Tapering is a gradual reduction in Kratom dosage, allowing the body to adjust and minimizing withdrawal symptoms. Here’s a step-by-step approach to tapering:

- Step 1: Assess your current use by keeping a daily log of your Kratom intake.

- Step 2: Set a tapering schedule, planning a gradual reduction of 10-20% per week.

- Step 3: Stay consistent with the schedule and avoid sudden drops in dosage.

- Step 4: Monitor withdrawal symptoms and adjust the tapering rate if necessary.

2. Switching Strains: Rotating different strains of Kratom can prevent the body from developing a strong tolerance to one particular type, making it easier to reduce overall intake.

3. Reducing Frequency: Gradually increase the time intervals between doses to help the body adjust to less frequent use.

4. Using Supplements: Certain supplements, such as magnesium for muscle aches and valerian root for sleep issues, can help manage withdrawal symptoms. Consult with a healthcare professional before adding supplements to your regimen.

Lifestyle Changes to Support Recovery:

1. Physical Activity: Regular exercise can boost endorphin levels, improving mood and reducing cravings.

2. Healthy Diet: A balanced diet rich in vitamins and minerals supports the body during recovery. Foods high in antioxidants and protein can aid in cellular and muscle recovery.

3. Sleep Hygiene: Establishing a regular sleep schedule can combat insomnia associated with Kratom withdrawal.

4. Mindfulness and Stress Management: Practices such as meditation, deep breathing exercises, and mindfulness can reduce stress and anxiety.

5. Support Systems: Engage with supportive friends, family, or support groups to share experiences and challenges.

Professional Support and Treatment Options:

1. Consulting Healthcare Professionals: Seek guidance from healthcare providers who understand Kratom addiction. They can offer personalized tapering schedules and medical support.

2. Therapy and Counseling: Behavioral therapies, such as cognitive-behavioral therapy (CBT), can help address the psychological aspects of addiction.

3. Inpatient and Outpatient Treatment Programs: For severe addiction, structured treatment programs offer intensive support.

4. Medication-Assisted Treatment (MAT): Medications may be prescribed to manage withdrawal symptoms and reduce cravings under professional supervision.

Steps to Prevent Relapse:

1. Identify Triggers: Recognize situations, people, or emotions that trigger the desire to use Kratom.

2. Develop a Relapse Prevention Plan: Create a detailed plan outlining steps to take if you feel the urge to use Kratom.

3. Continued Support: Stay connected with support groups, counselors, and healthcare providers even after reducing or stopping Kratom use.

4. Healthy Lifestyle Maintenance: Continue practicing the healthy habits developed during recovery.

A hopeful sunrise, beatiful scenery

Balancing the Benefits and Risks of Kratom

Understanding Kratom's biochemistry and potential for addiction is crucial for leveraging its benefits responsibly. By promoting responsible use, public education, and ongoing research, we can harness Kratom's therapeutic potential without it becoming a hindrance in users' lives.

Advocacy groups like the American Kratom Association (AKA) play a pivotal role in this journey. Their efforts to educate the public, advocate for sensible regulations, and support scientific research are crucial for Kratom's integration into mainstream healthcare as a natural alternative for pain management and addiction treatment.

In conclusion, Kratom's potential benefits are significant, but they come with challenges that must be addressed through education, responsible use, and ongoing research. By embracing a balanced approach, we can look forward to a future where Kratom is used safely and effectively, enhancing the lives of those who seek its benefits while minimizing the risks of addiction. The journey of Kratom is one of hope and promise, offering a path to wellness and recovery for many individuals worldwide.

Pure Lifted Kratom Logo



The information provided in this blog is for general informational purposes only and is not intended to constitute medical advice, diagnosis, or treatment. The content is based on research and personal experiences and is intended to promote awareness and understanding of Kratom and its potential benefits and risks.

Kratom vendors do not make any medical claims regarding the effectiveness or safety of Kratom. Kratom has not been evaluated or approved by the Food and Drug Administration (FDA) for any medical use, and its safety and efficacy are not guaranteed. Users should consult with a qualified healthcare provider before starting any new supplement or treatment, including Kratom.

The statements made in this blog are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary, and the use of Kratom should be undertaken with caution and under the supervision of a healthcare professional.

This blog and the vendor assume no responsibility for any adverse effects or consequences resulting from the use of Kratom. By reading this blog, you acknowledge and agree that the vendor is not liable for any claims, losses, or damages arising from your use of the information provided herein.

Please consult with your healthcare provider before making any decisions regarding your health and well-being. This blog does not endorse or recommend any particular treatment, medication, or product.

Contact Information

For more information or if you have any questions, please contact Pure Lifted at

5 views0 comments


bottom of page